Morton L P, Reynolds L, Zent R, Rayner B L
Department of Logopaedics, Groote Schuur Hospital, South Africa.
Adv Perit Dial. 1992;8:150-2.
Ultra high frequency (UHF, 10-20 kHz) and conventional audiometric thresholds (0,25-8 kHz) were obtained from 42 stable CAPD patients. Twenty-one (50%) and 11 (25%) of the patients had UHF and conventional hearing loss respectively, when compared to age related control data. This was unrelated to length of chronic renal failure and number of treatments with ototoxic drugs. Sixteen of these patients were monitored audiometrically using UHF during a course of vancomycin therapy for peritonitis. There was no significant change in hearing thresholds. In conclusion there is high incidence of hearing loss in CAPD patients which is unrelated to ototoxic drugs.
从42例稳定的持续性非卧床腹膜透析（CAPD）患者中获取了超高频（UHF，10 - 20千赫）和传统听力测定阈值（0.25 - 8千赫）。与年龄相关的对照数据相比，分别有21例（50%）和11例（25%）患者存在超高频听力损失和传统听力损失。这与慢性肾衰竭的病程长短以及使用耳毒性药物的治疗次数无关。在这些患者中，有16例在接受万古霉素治疗腹膜炎的过程中使用超高频进行听力监测。听力阈值没有显著变化。总之，CAPD患者中听力损失的发生率很高，且与耳毒性药物无关。
