Madrazo A, Polnitsky C A, Gianelli V
Arch Pathol Lab Med. 1976 Nov;100(11):576-82.
Biopsy specimens of the myocardium for electron microscopical study were taken from patients who were having surgical operations for correction of aortic and mitral valve lesions. Ultranstructural changes characteristic of hypertrophy and ischemia were found in the left ventricles of groups with aortic and mitral lesions. The severity of the cardiomyopathy was greater in hearts that had aortic lesions than in those that had mitral lesions. Both groups, however, displayed degenerative changes to an extent not readily appreciated or expected when their clinical histories and catheterization data were obtained.
用于电子显微镜研究的心肌活检标本取自正在接受主动脉瓣和二尖瓣病变矫正手术的患者。在患有主动脉瓣和二尖瓣病变的组别的左心室中发现了肥大和缺血特征性的超微结构变化。患有主动脉瓣病变的心脏的心肌病严重程度高于患有二尖瓣病变的心脏。然而，当获取两组患者的临床病史和导管检查数据时，两组均显示出在一定程度上不易察觉或预期的退行性变化。
