Kiefer G, Sandritter W
Beitr Pathol. 1976 Sep;158(4):332-62. doi: 10.1016/s0005-8165(76)80134-5.
The cell cycle and its significance for pathology is reviewed. The molecular basis and questions of regulation in the cell cycle are discussed, along with deviations from the normal cycle in the form of polyploidy formation and aneuploidy in tumor cells. Automated prescreening processes may play a role in the future in daily routine diagnosis. Methods of cytophotometry with the possibility for objective pattern recognition will become significant in pathology in many ways, both in research and in routine work.
本文综述了细胞周期及其在病理学中的意义。讨论了细胞周期的分子基础和调控问题,以及肿瘤细胞中多倍体形成和非整倍体等与正常周期的偏差。自动化预筛选过程未来可能在日常诊断中发挥作用。具有客观模式识别可能性的细胞光度测量方法在病理学的研究和日常工作中都将在许多方面变得至关重要。