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[国立卫生科学研究所的生育酚参考标准品(对照品911)]

[Tocopherol reference standard (Control 911) of the National Institute of Hygienic Sciences].

作者信息

Izumi W, Murai M, Komatsu H, Ishimitsu S, Okada S

出版信息

Eisei Shikenjo Hokoku. 1992(110):110-2.

PMID:1364418
Abstract

The raw material for tocopherol was tested for preparation of the "Tocopherol Reference Standard (Control 911)". Analytical data obtained were as follows: infrared spectrum, same as Tocopherol Reference Standard (Control 881); absorptivity, E1%1cm (292nm) = 75.5; thin-layer chromatography, no impurities were detected up to 50.0 micrograms; high performance liquid chromatography (HPLC), four impurities were detected; assay, 100.7% by HPLC. Based on the above results, the raw material was authorized as the Japanese Pharmacopoeia Standard (Control 911).

摘要

对生育酚的原料进行了“生育酚对照品(对照 911)”制备的测试。获得的分析数据如下:红外光谱,与生育酚对照品(对照 881)相同;吸光度,E1%1cm(292nm)=75.5;薄层色谱法,在 50.0 微克时未检测到杂质;高效液相色谱法(HPLC),检测到四种杂质;含量测定,通过 HPLC 为 100.7%。基于上述结果,该原料被批准为日本药典标准(对照 911)。

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