具有镇痛活性的2-芳基-3-苯基氨基-4,5-二氢-2H-苯并[g]吲唑
2-aryl-3-phenylamino-4,5-dihydro-2h-benz[g]indazoles with analgesic activity.
作者信息
Schenone Silvia, Bruno Olga, Ranise Angelo, Brullo Chiara, Bondavalli Francesco, Filippelli Walter, Mazzeo Filomena, Capuano Annalisa, Falcone Giuseppe
机构信息
Dipartimento di Scienze Farmaceutiche, Facoltà di Farmacia dell'Università degli Studi di Genova, Viale Benedetto XV, 3, 16132, Genova, Italy.
出版信息
Farmaco. 2003 Sep;58(9):845-9. doi: 10.1016/S0014-827X(03)00142-3.
Abstract
A series of 2-aryl-3-phenylamino-4,5-dihydro-2H-benz[g]indazoles was synthesized and tested for antiarrhythmic, local anaesthetic and analgesic activity. The title compounds showed a good antinociceptive activity.
摘要
合成了一系列2-芳基-3-苯基氨基-4,5-二氢-2H-苯并[g]吲唑，并对其抗心律失常、局部麻醉和镇痛活性进行了测试。标题化合物显示出良好的抗伤害感受活性。
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