• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

异硫代氨基脲及其环状类似物结构修饰的生物学效应研究。

An investigation of the biological effect of structural modifications of isothiosemicarbazones and their cyclic analogues.

作者信息

Maccioni E, Cardia M C, Distinto S, Bonsignore L, De Logu A

机构信息

Dipartimento Farmaco Chimico Tecnologico, Universita degli Studi di Cagliari, Via Ospedale, 72, 09124 Cagliari, Italy.

出版信息

Farmaco. 2003 Sep;58(9):951-9. doi: 10.1016/S0014-827X(03)00154-X.

DOI:10.1016/S0014-827X(03)00154-X
PMID:13679191
Abstract

Several arylideneisothiosemicarbazones and arylidenehydrazothiazoles have been synthesised to obtain new antimicrobial agents. Their activity against both bacteria and fungi has been tested and some interesting informations about their biological activity have been obtained.

摘要

已合成了几种亚芳基异硫脲腙和亚芳基肼噻唑，以获得新型抗菌剂。已测试了它们对细菌和真菌的活性，并获得了一些有关其生物活性的有趣信息。

相似文献

1
An investigation of the biological effect of structural modifications of isothiosemicarbazones and their cyclic analogues.异硫代氨基脲及其环状类似物结构修饰的生物学效应研究。
Farmaco. 2003 Sep;58(9):951-9. doi: 10.1016/S0014-827X(03)00154-X.
2
Copper complexes of imidazole-2-, pyrrole-2- and indol-3-carbaldehyde thiosemicarbazones: inhibitory activity against fungi and bacteria.咪唑 -2-、吡咯 -2- 和吲哚 -3- 甲醛缩氨基硫脲的铜配合物：对真菌和细菌的抑制活性。
J Inorg Biochem. 2005 Nov;99(11):2231-9. doi: 10.1016/j.jinorgbio.2005.07.018. Epub 2005 Sep 26.
3
Synthesis of thiosemicarbazones derived from N-(4-hippuric acid)thiosemicarbazide and different carbonyl compounds as antimicrobial agents.N-(4-马尿酸基)缩氨硫脲席夫碱及其衍生物的合成与抗菌活性研究
Eur J Med Chem. 2013 Sep;67:263-8. doi: 10.1016/j.ejmech.2013.06.031. Epub 2013 Jun 21.
4
Synthesis and anti-microbial activity of isothiosemicarbazones and cyclic analogues.异硫代氨基脲及其环状类似物的合成与抗菌活性
Farmaco. 2002 Oct;57(10):809-17. doi: 10.1016/s0014-827x(02)01288-0.
5
Antimicrobial activity of 2,4-dihydro-[1,2,4]triazol-3-one derivatives.2,4-二氢-[1,2,4]三唑-3-酮衍生物的抗菌活性
Pol J Microbiol. 2008;57(2):179-82.
6
Synthesis of platensimycin analogues and their antibiotic potency.扁枝衣霉素类似物的合成及其抗菌效力。
Arch Pharm (Weinheim). 2008 Jun;341(6):386-92. doi: 10.1002/ardp.200700177.
7
Synthesis, biological evaluation of new oxazolidino-sulfonamides as potential antimicrobial agents.合成、新的恶唑烷酮-磺胺类化合物的生物评价作为有潜力的抗菌剂。
Eur J Med Chem. 2013 Apr;62:661-9. doi: 10.1016/j.ejmech.2013.01.034. Epub 2013 Feb 5.
8
Design, synthesis, and biological evaluation of 1,2,3-trisubstituted-1,4-dihydrobenzo[g]quinoxaline-5,10-diones and related compounds as antifungal and antibacterial agents.1,2,3-三取代-1,4-二氢苯并[g]喹喔啉-5,10-二酮及相关化合物作为抗真菌和抗菌剂的设计、合成与生物学评价
Bioorg Med Chem. 2006 Sep 1;14(17):6120-6. doi: 10.1016/j.bmc.2006.04.029. Epub 2006 Jun 27.
9
Synthesis and antimicrobial studies of novel 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-one 4'-phenylthiosemicarbazones.新型 2,4-二芳基-3-氮杂双环[3.3.1]壬烷-9-酮 4'-苯硫代缩氨基脲的合成及抗菌研究。
J Enzyme Inhib Med Chem. 2011 Jun;26(3):430-9. doi: 10.3109/14756366.2010.525508. Epub 2010 Oct 28.
10
Antimicrobial activity of Schinus lentiscifolius (Anacardiaceae).金桃叶珊瑚的抗菌活性（漆树科）。
J Ethnopharmacol. 2013 Jul 9;148(2):486-91. doi: 10.1016/j.jep.2013.04.043. Epub 2013 May 14.

引用本文的文献

1
One-Pot Synthesis of Novel Thiazoles as Potential Anti-Cancer Agents.一锅法合成新型噻唑类化合物作为潜在的抗癌剂。
Drug Des Devel Ther. 2020 Apr 3;14:1363-1375. doi: 10.2147/DDDT.S221263. eCollection 2020.
2
Synthesis and Biological Evaluation of Bisthiazoles and Polythiazoles.双噻唑和聚噻唑的合成与生物评价。
Molecules. 2018 May 10;23(5):1133. doi: 10.3390/molecules23051133.
3
The synthesis and antiproliferative activities of new arylidene-hydrazinyl-thiazole derivatives.新型亚芳基肼基噻唑衍生物的合成及其抗增殖活性
Int J Mol Sci. 2014 Dec 1;15(12):22059-72. doi: 10.3390/ijms151222059.
4
(E)-1-(3-Eth-oxy-2-hy-droxy-benzyl-idene)thio-semicarbazide.（E）-1-（3-乙氧基-2-羟基亚苄基）硫代氨基脲
Acta Crystallogr Sect E Struct Rep Online. 2012 Feb 1;68(Pt 2):o340-1. doi: 10.1107/S1600536812000487. Epub 2012 Jan 11.
5
(E)-1-(2-Hy-droxy-5-meth-oxy-benzyl-idene)thio-semicarbazide.（E）-1-（2-羟基-5-甲氧基-亚苄基）硫代氨基脲
Acta Crystallogr Sect E Struct Rep Online. 2012 Feb 1;68(Pt 2):o324-5. doi: 10.1107/S1600536811056182. Epub 2012 Jan 11.
6
5-Bromo-2-hy-droxy-benzaldehyde thio-semicarbazone.5-溴-2-羟基苯甲醛缩氨基硫脲
Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 31;66(Pt 11):o2999. doi: 10.1107/S1600536810043357.
7
5-Chloro-2-hy-droxy-benzaldehyde thio-semicarbazone.5-氯-2-羟基苯甲醛缩氨基硫脲
Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 30;66(Pt 11):o2981. doi: 10.1107/S1600536810043448.
8
3-Methoxy-benzaldehyde thio-semi-carbazone.3-甲氧基苯甲醛硫代半卡巴腙
Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 28;65(Pt 4):o884. doi: 10.1107/S160053680901040X.
9
4-Methyl-benzaldehyde thio-semi-carbazone.4-甲基苯甲醛硫代半卡巴腙
Acta Crystallogr Sect E Struct Rep Online. 2009 Aug 26;65(Pt 9):o2244. doi: 10.1107/S1600536809033297.
10
Effects of a thiosemicarbazide camphene derivative on Trichophyton mentagrophytes.一种氨基硫脲莰烯衍生物对须癣毛癣菌的作用
Molecules. 2009 May 13;14(5):1796-807. doi: 10.3390/molecules14051796.