Gupta Archana, Ampofo Krow, Rubenstein David, Saiman Lisa
Division of Neonatology, Department of Pediatrics, The Children's Hospital of New York, New York Presbyterian Medical Center, New York, NY 10032, USA.
J Perinatol. 2003 Sep;23(6):439-43. doi: 10.1038/sj.jp.7210973.
Infections caused by extended-spectrum beta-lactamase (ESBL)-producing pathogens, particularly Klebsiella pneumoniae, are increasing. The epidemiology of ESBL-producing K. pneumoniae, the mechanisms of resistance, and treatment strategies for infections caused by these organisms are reviewed.
由产超广谱β-内酰胺酶(ESBL)的病原体引起的感染,尤其是肺炎克雷伯菌引起的感染正在增加。本文综述了产ESBL肺炎克雷伯菌的流行病学、耐药机制以及由这些微生物引起的感染的治疗策略。