Ososki Andreana L, Kennelly Edward J
Biological Sciences, Lehman College, City University of New York, 250 Bedford Park Blvd West, Bronx, NY 10468, USA.
Phytother Res. 2003 Sep;17(8):845-69. doi: 10.1002/ptr.1364.
Phytoestrogens are a diverse group of plant-derived compounds that structurally or functionally mimic mammalian estrogens and show potential benefits for human health. The number of articles published on phytoestrogens has risen dramatically in the past couple decades. Further research continues to demonstrate the biological complexity of phytoestrogens, which belong to several different chemical classes and act through diverse mechanisms. This paper discusses the classification of phytoestrogens, methods of identification, their proposed mechanisms of action and botanical sources for phytoestrogens. The effects of phytoestrogens on breast and prostate cancers, cardiovascular disease, menopausal symptoms and osteoporosis will also be examined including research on benefits and risks.
植物雌激素是一类源自植物的多样化化合物,它们在结构或功能上模拟哺乳动物雌激素,并对人类健康显示出潜在益处。在过去几十年中,关于植物雌激素的发表文章数量急剧增加。进一步的研究不断证明植物雌激素的生物学复杂性,它们属于几个不同的化学类别,并通过多种机制发挥作用。本文讨论了植物雌激素的分类、鉴定方法、其假定的作用机制以及植物雌激素的植物来源。还将研究植物雌激素对乳腺癌、前列腺癌、心血管疾病、更年期症状和骨质疏松症的影响,包括对益处和风险的研究。