Vieira G, Ferreira P M, Matos L G, Ferreira E C, Rodovalho W, Ferri P H, Ferreira H D, Costa E A
Instituto de Ciências Biológicas, Departamento de Ciências Fisiológicas, Universidade Federal de Goiás, Goiânia, Brazil.
Phytother Res. 2003 Sep;17(8):892-6. doi: 10.1002/ptr.1247.
The croton oil-induced mouse ear oedema test, acetic acid-induced abdominal writhing, and carrageenan-induced peritonitis were used to study the anti-inflammatory effects of the crude ethanol extract and its alkaloid fraction from Solanum lycocarpum fruits. The alkaloid fraction induced a dose-dependent reduction in ear oedema formation and leukocyte migration, suggesting that S. lycocarpum fruits may contain steroidal alkaloids accounting for the anti-inflammatory effect of the crude ethanol extract.
采用巴豆油诱导的小鼠耳肿胀试验、醋酸诱导的扭体反应和角叉菜胶诱导的腹膜炎来研究番茄果实粗乙醇提取物及其生物碱部分的抗炎作用。生物碱部分可使耳肿胀形成和白细胞迁移呈剂量依赖性降低，这表明番茄果实可能含有甾体生物碱，这是粗乙醇提取物具有抗炎作用的原因。
