Ficker C, Smith M L, Akpagana K, Gbeassor M, Zhang J, Durst T, Assabgui R, Arnason J T
Ottawa-Carleton Institutes of Biology and Chemistry, Carleton University and University of Ottawa, Ottawa ON, Canada.
Phytother Res. 2003 Sep;17(8):897-902. doi: 10.1002/ptr.1335.
A bioassay-guided isolation of antifungal compounds from an African land race of ginger, Zingiber officinale Roscoe, led to the identification of [6], [8] and [10]-gingerols and [6]-gingerdiol as the main antifungal principles. The compounds were active against 13 human pathogens at concentrations of <1 mg/mL. The gingerol content of the African land race was at least 3 x higher than that of typical commercial cultivars of ginger. Therefore, ginger extracts standardized on the basis of the identified compounds, could be considered as antifungal agents for practical therapy.
通过生物测定法从非洲地方品种姜（姜科姜属植物姜Zingiber officinale Roscoe）中分离抗真菌化合物，鉴定出[6] -、[8] -和[10] -姜酚以及[6] -姜二醇为主要抗真菌成分。这些化合物在浓度<1 mg/mL时对13种人类病原体具有活性。该非洲地方品种姜的姜酚含量至少比典型的商业姜品种高3倍。因此，基于已鉴定化合物标准化的姜提取物可被视为实际治疗中的抗真菌剂。
