关于软骨对无机硫酸盐渗透性的研究。
A consideration of the permeability of cartilage to inorganic sulfate.
作者信息
CAMPO R D, DZIEWIATKOWSKI D D
出版信息
J Biophys Biochem Cytol. 1961 Feb;9(2):401-8. doi: 10.1083/jcb.9.2.401.
Abstract
On the basis of an examination of autoradiograms of knee-joints fixed so as to remove chondroitin sulfate or inorganic sulfate, or to minimize the loss of both, it is suggested that the cartilage is permeable to inorganic sulfate in vivo and in vitro. In vivo and in vitro, almost as rapidly as it enters the cartilage, inorganic sulfate is utilized by the cells in the synthesis of chondroitin sulfate. The net result is a continuing low concentration of inorganic sulfate in the cartilage.
摘要
通过对固定膝关节的放射自显影片进行检查，以去除硫酸软骨素或无机硫酸盐，或尽量减少两者的损失，结果表明，软骨在体内和体外对无机硫酸盐都是可渗透的。在体内和体外，无机硫酸盐几乎一进入软骨就被细胞用于硫酸软骨素的合成。最终结果是软骨中无机硫酸盐的浓度持续较低。
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