Alanen A, Kallio T, Lehto I, Wiernsperger N
Department of Diagnostic Radiology, Turku University Central Hospital, Finland.
J Cardiovasc Pharmacol. 1990;16 Suppl 3:S33-5.
Red blood cell aggregates are mainly responsible for the echogenicity of flowing blood. Thus, ultrasound can be used to observe the degree of red blood cell aggregation in slow flow conditions. We quantified blood echogenicity to study aggregation tendency of red blood cells in blood of patients with claudication, patients with suspected venous thrombosis, and normal volunteers without and with in vitro addition of naftidrofuryl (10(-6) M). Normal volunteers showed lower original echogenicity than any group of patients, and claudication patients showed the highest echogenicity. Naftidrofuryl caused a fall in mean echogenicity in all groups, and its effect was pronounced on blood samples with a high original echogenicity.
红细胞聚集体是血流回声的主要来源。因此，超声可用于观察慢血流状态下红细胞的聚集程度。我们通过量化血液回声来研究间歇性跛行患者、疑似静脉血栓形成患者以及正常志愿者（体外添加萘呋胺酯（10⁻⁶ M）前后）血液中红细胞的聚集倾向。正常志愿者的原始回声低于任何一组患者，而间歇性跛行患者的回声最高。萘呋胺酯使所有组的平均回声降低，且对原始回声较高的血样影响显著。
