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年龄相关性黄斑变性中黄斑中心凹下新生血管膜的手术切除

Surgical excision of subfoveal neovascular membranes in age-related macular degeneration.

作者信息

Lambert H M, Capone A, Aaberg T M, Sternberg P, Mandell B A, Lopez P F

机构信息

Department of Ophthalmology, Emory University, Atlanta, Georgia.

出版信息

Am J Ophthalmol. 1992 Mar 15;113(3):257-62. doi: 10.1016/s0002-9394(14)71576-4.

Abstract

We studied the results of surgical excision of ten consecutive subfoveal choroidal neovascular membranes in ten patients with age-related macular degeneration. The criteria for surgical eligibility included the following: (1) a clearly identifiable subfoveal membrane occupying the entire foveal avascular zone, (2) a visual acuity of 20/200 or worse, (3) minimal subretinal hemorrhage, and (4) an associated exudative macular detachment. Six of the ten patients showed visual improvement at one-month and three-month follow-up visits and seven showed visual improvement by the six-month examination. All ten maculae remained attached without recurrence of subfoveal neovascular membranes throughout the follow-up period. These results suggested that surgical excision is a viable alternative to laser photocoagulation in patients with subfoveal neovascularization in age-related macular degeneration.

摘要

我们研究了连续10例年龄相关性黄斑变性患者的10个黄斑中心凹下脉络膜新生血管膜的手术切除结果。手术适应证标准如下:(1)黄斑中心凹下有明确可辨的新生血管膜,占据整个黄斑中心凹无血管区;(2)视力为20/200或更差;(3)视网膜下少量出血;(4)伴有渗出性黄斑脱离。10例患者中有6例在术后1个月和3个月随访时视力改善,7例在6个月检查时视力改善。在整个随访期内,所有10个黄斑均保持贴附状态,黄斑中心凹下新生血管膜无复发。这些结果表明,对于年龄相关性黄斑变性黄斑中心凹下新生血管形成的患者,手术切除是激光光凝治疗的一种可行替代方法。

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