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Protein kinase C: a target for anti-inflammatory therapy?

作者信息

Amon U, Dietz K R

机构信息

Department of Dermatology, Medical University of Lübeck, Federal Republic of Germany.

出版信息

Arch Dermatol Res. 1992;284(1):8-10. doi: 10.1007/BF00371919.

DOI:10.1007/BF00371919
PMID:1372797
Abstract
摘要

相似文献

1
Protein kinase C: a target for anti-inflammatory therapy?
Arch Dermatol Res. 1992;284(1):8-10. doi: 10.1007/BF00371919.
2
Effect of staurosporine on histamine release from rat serosal mast cells.星形孢菌素对大鼠浆膜肥大细胞组胺释放的影响。
Ann Allergy. 1989 Sep;63(3):231-4.
3
Modulation of human basophil histamine release by protein kinase C inhibitors differs with secretagogue and with inhibitor.蛋白激酶C抑制剂对人嗜碱性粒细胞组胺释放的调节作用因促分泌剂和抑制剂的不同而有所差异。
J Pharmacol Exp Ther. 1992 Mar;260(3):1028-37.
4
Differential inhibition of histamine release from mast cells by protein kinase C inhibitors: staurosporine and K-252a.蛋白激酶C抑制剂（星形孢菌素和K-252a）对肥大细胞组胺释放的差异性抑制作用
Biochem Pharmacol. 1990 Aug 1;40(3):447-56. doi: 10.1016/0006-2952(90)90542-s.
5
Effects of protein kinase C and phospholipase C inhibitors on IgE-dependent and IgE-independent basophil histamine release.蛋白激酶C和磷脂酶C抑制剂对IgE依赖性和IgE非依赖性嗜碱性粒细胞组胺释放的影响。
Inflamm Res. 2000 Sep;49(9):480-5. doi: 10.1007/s000110050620.
6
Effect of a potent selective protein kinase C inhibitor on histamine release from rat mast cells.
J Pharm Sci. 1993 Feb;82(2):209-10. doi: 10.1002/jps.2600820219.
7
Differentiation of second messenger systems in mast cell activation.肥大细胞激活过程中第二信使系统的分化
Agents Actions. 1989 Jun;27(3-4):410-3. doi: 10.1007/BF01972837.
8
Effects of inhibitors of protein kinase C on the release and synthesis of histamine in rat basophilic leukemia cells (2H3).
Jpn J Pharmacol. 1992 Mar;58(3):291-8. doi: 10.1254/jjp.58.291.
9
Protein kinase C modulates immunoglobulin E-mediated activation of human mast cells from lung and skin. I. Pharmacologic inhibition.蛋白激酶C调节免疫球蛋白E介导的来自肺和皮肤的人肥大细胞的激活。I. 药理学抑制作用。
J Pharmacol Exp Ther. 1991 Sep;258(3):824-9.
10
Signal transduction events in human basophils. A comparative study of the role of protein kinase C in basophils activated by anti-IgE antibody and formyl-methionyl-leucyl-phenylalanine.人嗜碱性粒细胞中的信号转导事件。蛋白激酶C在抗IgE抗体和甲酰甲硫氨酰亮氨酰苯丙氨酸激活的嗜碱性粒细胞中作用的比较研究。
J Immunol. 1990 Sep 15;145(6):1897-905.

引用本文的文献

1
Functional comparison of different histamine-containing IgE-receptor positive cells.不同含组胺的IgE受体阳性细胞的功能比较
Agents Actions. 1994 Jun;41 Spec No:C28-9. doi: 10.1007/BF02007752.
2
Pharmacological investigations with different protein kinase C inhibitors on IgE-dependent and IgE-independent activation of human basophils.使用不同蛋白激酶C抑制剂对人嗜碱性粒细胞IgE依赖性和IgE非依赖性激活进行的药理学研究。
Agents Actions. 1993 May;39(1-2):13-9. doi: 10.1007/BF01975708.

本文引用的文献

1
Basophils in human disease.人类疾病中的嗜碱性粒细胞。
Clin Rev Allergy. 1983 Sep;1(3):427-48. doi: 10.1007/BF02991231.
2
Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase.星形孢菌素，一种磷脂/钙离子依赖性蛋白激酶的强效抑制剂。
Biochem Biophys Res Commun. 1986 Mar 13;135(2):397-402. doi: 10.1016/0006-291x(86)90008-2.
3
A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity.星形孢菌素的一种衍生物（CGP 41 251）对蛋白激酶C抑制具有选择性，且具有体外抗增殖和体内抗肿瘤活性。
Int J Cancer. 1989 May 15;43(5):851-6. doi: 10.1002/ijc.2910430519.
4
Protein kinase C (PKC) changes in human basophils. IgE-mediated activation is accompanied by an increase in total PKC activity.人嗜碱性粒细胞中蛋白激酶C（PKC）的变化。IgE介导的激活伴随着总PKC活性的增加。
J Immunol. 1989 Mar 1;142(5):1669-77.
5
Human skin mast cells: their dispersion, purification, and secretory characterization.人皮肤肥大细胞：其分散、纯化及分泌特性
J Immunol. 1987 Feb 1;138(3):861-7.
6
Protein kinase C in transmembrane signalling.跨膜信号传导中的蛋白激酶C
FEBS Lett. 1990 Aug 1;268(2):350-4. doi: 10.1016/0014-5793(90)81284-u.
7
The mast cell in health and disease.健康与疾病中的肥大细胞。
J Am Acad Dermatol. 1990 Oct;23(4 Pt 1):615-24. doi: 10.1016/0190-9622(90)70264-i.
8
Differential inhibition of histamine release from mast cells by protein kinase C inhibitors: staurosporine and K-252a.蛋白激酶C抑制剂（星形孢菌素和K-252a）对肥大细胞组胺释放的差异性抑制作用
Biochem Pharmacol. 1990 Aug 1;40(3):447-56. doi: 10.1016/0006-2952(90)90542-s.
9
Potent and specific inhibitors of protein kinase C of microbial origin.微生物来源的蛋白激酶C的强效特异性抑制剂。
Biotechnology (N Y). 1990 Aug;8(8):732-5. doi: 10.1038/nbt0890-732.