Roth B J, Pascual-Leone A, Cohen L G, Hallett M
Biomedical Engineering and Instrumentation Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Electroencephalogr Clin Neurophysiol. 1992 Apr;85(2):116-23. doi: 10.1016/0168-5597(92)90077-o.
The temperature of electrodes and metal disks positioned close to a coil was measured during rapid-rate magnetic stimulation. The temperature rise ranged from a fraction of a degree to almost half a degree per stimulus pulse and increased with the electrical conductivity of the metal, the square of the electrode radius and the square of the stimulus strength, and was independent of the electrode thickness. During a brief high-frequency train, the temperature increase from each pulse added; during a long, high-frequency train the temperature increase approached a steady state. After the stimulus ended, an electrode on the arm cooled with a time constant of about 45 sec. A standard silver EEG electrode on the surface of the skin did not increase in temperature enough to induce a skin burn if the stimulating rate was below 0.4 Hz or the total number of stimuli was less than 20. Heating was reduced by cutting gaps in the electrode.
在快速率磁刺激过程中,对靠近线圈放置的电极和金属盘的温度进行了测量。每个刺激脉冲引起的温度上升范围从不到一度到近半度不等,且随金属的电导率、电极半径的平方以及刺激强度的平方而增加,与电极厚度无关。在短暂的高频序列刺激期间,每个脉冲引起的温度上升会叠加;在长时间的高频序列刺激期间,温度上升接近稳态。刺激结束后,手臂上的电极以约45秒的时间常数冷却。如果刺激速率低于0.4Hz或刺激总数少于20次,皮肤表面的标准银质脑电图电极温度升高不足以引起皮肤灼伤。通过在电极上切割缝隙可减少发热。