Büschges A, Ramirez J M, Driesang R, Pearson K G
Department of Physiology, University of Alberta, Edmonton, Canada.
J Neurobiol. 1992 Feb;23(1):44-60. doi: 10.1002/neu.480230106.
The flight motor pattern of the adult locust (Locusta migratoria L.) is able to recover from the loss of the hindwing tegulae. This recovery is due to a functional substitution of the hindwing tegulae by the forewing tegulae (Büschges, Ramirez, and Pearson, 1992). To assess changes in the pathways from the forewing tegulae in the flight system, we investigated the pathways of the forewing tegula in intact locusts and in animals 2 weeks after hindwing tegula removal. The following physiological alterations in these pathways were found to be associated with the recovery: (1) In the intact locusts, the connections of forewing tegula afferents to flight interneurons are variable but this variability did not occur in recovered animals, and (2) larger numbers of forewing tegula afferents connect to interneurons that excite elevator motoneurons (interneurons 566 and 567) and to an interneuron that inhibits depressor motoneurons (interneuron 511). The size of unitary excitatory postsynaptic potentials (EPSPs) evoked by signal forewing tegula afferents was found not to be altered in recovered animals. The changes in connectivity of forewing tegula afferents are correlated with morphological alterations in the structure of the terminal processes of the afferents and with sprouting of some branches of interneurons receiving input from these afferents.
成年蝗虫（飞蝗）的飞行运动模式能够从后翅翅轭缺失的状态中恢复。这种恢复是由于前翅翅轭对后翅翅轭进行了功能替代（比施格斯、拉米雷斯和皮尔逊，1992年）。为了评估飞行系统中来自前翅翅轭的通路变化，我们研究了完整蝗虫以及后翅翅轭移除两周后的动物体内前翅翅轭的通路。发现这些通路中的以下生理变化与恢复过程有关：（1）在完整的蝗虫中，前翅翅轭传入神经元与飞行中间神经元的连接是可变的，但在恢复的动物中这种变异性并未出现；（2）更多数量的前翅翅轭传入神经元与兴奋提升运动神经元的中间神经元（中间神经元566和567）以及与抑制下压运动神经元的中间神经元（中间神经元511）相连。发现信号前翅翅轭传入神经元诱发的单突触兴奋性突触后电位（EPSP）的大小在恢复的动物中并未改变。前翅翅轭传入神经元连接性的变化与传入神经元终末突起结构的形态学改变以及接收这些传入神经元输入的中间神经元一些分支的出芽有关。
