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内镜下乳头切开术治疗伴有胆总管扩张和小胆囊结石的胆道疼痛及波动性胆汁淤积

Endoscopic papillotomy in biliary tract pain and fluctuating cholestasis with common bile duct dilatation and small gallbladder stones.

作者信息

Boender J, van Blankenstein M, Nix G A, Wilson J H, Dees J

机构信息

Department of Diagnostic Radiology, University Hospital, Rotterdam-Dijkzigt, The Netherlands.

出版信息

Endoscopy. 1992 Mar;24(3):203-7. doi: 10.1055/s-2007-1010463.

DOI:10.1055/s-2007-1010463
PMID:1375152
Abstract

In patients suspected of having functional disorders of the papilla it is often difficult to establish the indications whether or not to perform endoscopic papillotomy (EP). We report on thirty-two consecutive patients referred for endoscopic retrograde cholangiopancreatography who all had longstanding biliary tract pain and episodes of liver enzyme elevation indicating cholestasis. Further features were: 1) a dilated common bile duct (CBD) after cholecystectomy (n = 11) or 2) a dilated CBD without or with larger (greater than cystic duct diameter) gallbladder stones (n = 6) or 3) multiple small gallbladder stones, with a normal or dilated CBD, in patients with signs of acute gallstone pancreatitis or in whom elective cholecystectomy was not indicated (n = 15). No CBD stones, organic obstruction or other disorders were found in these patients. Without further diagnostic procedures, EP was routinely performed. The laboratory (up to 3 months) and clinical findings (2 to 4 years follow up) showed improvement in all patients undergoing EP. We conclude that immediate EP appears justified in these selected patients.

摘要

对于疑似患有乳头功能紊乱的患者,往往难以确定是否进行内镜乳头切开术(EP)的指征。我们报告了连续32例因内镜逆行胰胆管造影术前来就诊的患者,他们均有长期的胆道疼痛和肝酶升高发作,提示胆汁淤积。其他特征包括:1)胆囊切除术后胆总管(CBD)扩张(n = 11);2)无胆囊结石或有较大(大于胆囊管直径)胆囊结石时CBD扩张(n = 6);3)在有急性胆石性胰腺炎体征或不适合择期胆囊切除术的患者中,有多个小胆囊结石,CBD正常或扩张(n = 15)。这些患者未发现CBD结石、器质性梗阻或其他疾病。未经进一步诊断程序,常规进行EP。实验室检查结果(长达3个月)和临床发现(随访2至4年)显示,所有接受EP的患者均有改善。我们得出结论,在这些选定的患者中立即进行EP似乎是合理的。

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