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[内镜逆行胰胆管造影术中胆总管扩张但无明显梗阻。描述与进展]

[Dilatation of the common bile duct without visible obstruction at endoscopic retrograde cholangiography. Description and development].

作者信息

Seyrig J A, Liguory C, Buffet C, Fabre M, Fritsch J, Choury A, Ladouch-Badre A, Liguory-Brunaud M D, Etienne J P

机构信息

Service d'Hépato-Gastroentérologie, Hôpital de Bicêtre, Le Kremlin-Bicêtre.

出版信息

Gastroenterol Clin Biol. 1988 May;12(5):459-64.

PMID:3402691
Abstract

The aim of this study was to specify the signs and course of patients with a dilated common bile duct without obstruction. We included patients with a dilated common bile duct of more than 12 mm on endoscopic retrograde cholangiography, and we excluded patients with stones, tumor or other visible obstruction. Two hundred and seven patients (8.4 p. 100 of endoscopic retrograde cholangiography) were included. One hundred and nineteen (57.5 p. 100) had undergone cholecystectomy. Sixty-five p. 100 of patients had signs suggesting biliary tract disease, and 78 p. 100 had biological signs of cholestasis. The size of the common bile duct was not different whether the patient had been cholecystectomized (16.2 +/- 0.3 mm.M +/- SEM) or not (16.2 +/- 0.4 mm). Forty-one patients in the non cholecystectomized group had gallbladder stones. Thus, 47 of our 207 patients (23 p. 100) had neither gallbladder stones nor previous cholecystectomy. Endoscopic retrograde cholangiography was completed by endoscopic sphincterotomy in 130 patients, either in the intent of not missing obstruction, or for therapeutic purposes. Follow-up more than one month after endoscopic retrograde cholangiography was available for 159 patients (77 p. 100). The median survival was 73 months. One hundred and ten patients (69 p. 100) were asymptomatic, 36 (23 p. 100) had atypical abdominal pain while 13 (8 p. 100) patients had episodes of biliary colic and/or fever and/or jaundice. During follow-up, an initially unrecognized obstacle was discovered in 8 patients: 5 common bile duct stones, 2 ampullary tumors and one pancreatic tumor.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本研究的目的是明确无梗阻性胆总管扩张患者的体征及病程。我们纳入了经内镜逆行胰胆管造影术显示胆总管扩张超过12mm的患者,并排除了有结石、肿瘤或其他明显梗阻的患者。共纳入207例患者(占经内镜逆行胰胆管造影术患者的8.4%)。其中119例(57.5%)接受过胆囊切除术。65%的患者有提示胆道疾病的体征,78%的患者有胆汁淤积的生物学体征。无论患者是否接受过胆囊切除术,胆总管的大小并无差异(接受过胆囊切除术患者的胆总管大小为16.2±0.3mm,均值±标准误;未接受过胆囊切除术患者的胆总管大小为16.2±0.4mm)。未接受过胆囊切除术的患者中有41例有胆囊结石。因此,我们的207例患者中有47例(23%)既没有胆囊结石也未接受过胆囊切除术。130例患者通过内镜括约肌切开术完成了经内镜逆行胰胆管造影术,目的是不遗漏梗阻情况或用于治疗。159例患者(77%)在经内镜逆行胰胆管造影术后有超过1个月的随访数据。中位生存期为73个月。110例患者(69%)无症状,36例(23%)有非典型腹痛,13例(8%)有胆绞痛和/或发热和/或黄疸发作。在随访期间,8例患者发现了最初未被识别的病变:5例胆总管结石、2例壶腹肿瘤和1例胰腺肿瘤。(摘要截选至250词)

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