Balabolkin M I, Khaiutina T L, Mkrtumian A M
Ross Med Zh. 1992(1):13-5.
Bone metabolism was investigated in toxic goiter. The authors obtained evidence on high levels of osteocalcin which marks bone formation. The time of the thyroid function recovery during thyrostatic therapy and indices of phosphorus-calcium metabolism disagree indicating delayed normalization of the bone tissue metabolism. There is a correlation between the thyroid function, osteocalcin and oxyproline that indirectly confirms the action of thyroid hormones on the bone matrix; between osteocalcin levels and other indices of bone metabolism (serum alkaline phosphatase activity and oxyproline excretion).
对毒性甲状腺肿患者的骨代谢进行了研究。作者获得了表明骨形成的骨钙素水平较高的证据。甲状腺功能在甲状腺抑制治疗期间恢复的时间与磷钙代谢指标不一致，这表明骨组织代谢的正常化延迟。甲状腺功能、骨钙素和羟脯氨酸之间存在相关性，这间接证实了甲状腺激素对骨基质的作用；骨钙素水平与骨代谢的其他指标（血清碱性磷酸酶活性和羟脯氨酸排泄）之间也存在相关性。
