Wise R, Andrews J M, Bedford K A
Chemotherapy. 1977;23(1):19-24. doi: 10.1159/000221966.
Forty strains of Bacteroides sp. were tested against three nitroimidazole compounds, metronidazole, tinidazole and nimorazole and the aminoglycosidic antibiotic spectinomycin. The effect of altering the inoculum and the presence of serum upon the minimum inhibitory concentration (MIC) was also noted. The three nitroimidazole compounds were all very active (average MIC = circa 0.25 mg/l). Tinidazole was twofold more active. The MIC of spectinomycin was 32 mg/l.
对40株拟杆菌属菌株进行了三种硝基咪唑类化合物（甲硝唑、替硝唑和尼莫唑）以及氨基糖苷类抗生素壮观霉素的测试。还记录了改变接种量和血清存在对最低抑菌浓度（MIC）的影响。三种硝基咪唑类化合物都非常有效（平均MIC约为0.25毫克/升）。替硝唑的活性高两倍。壮观霉素的MIC为32毫克/升。
