甲硝唑、替硝唑和尼莫唑对革兰氏阴性厌氧杆菌的体外活性比较。
A comparison of the in vitro activity of metronidazole, tinidazole, and nimorazole against Gram-negative anaerobic bacilli.
作者信息
Reynolds A V, Hamilton-Miller J M, Brumfitt W
出版信息
J Clin Pathol. 1975 Oct;28(10):775-8. doi: 10.1136/jcp.28.10.775.
Abstract
The in vitro activities of metronidazole, nimorazole, and tinidazole were compared against 69 strains of obligately anaerobic Gram-negative bacilli. Geometric mean MICs were 0-34, 1-05, and 0-28 mug/ml respectively. Thirty-six strains were also tested by the disk method. Correlation between MIC and diameter of the zones of inhibition was poor.
摘要
比较了甲硝唑、尼莫唑和替硝唑对69株专性厌氧革兰氏阴性杆菌的体外活性。几何平均MIC分别为0 - 34、1 - 05和0 - 28μg/ml。还用纸片法对36株菌株进行了测试。MIC与抑菌圈直径之间的相关性较差。
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