Mendelson B, Koerber H R, Frank E
Department of Neurobiology, Anatomy and Cell Science, University of Pittsburgh School of Medicine, PA 15261.
Neurosci Lett. 1992 Apr 13;138(1):72-6. doi: 10.1016/0304-3940(92)90475-m.
Muscle and cutaneous nerves were individually labeled with DiI in chick embryos to examine the development of sensory afferent arborizations in the spinal cord. Initially, cutaneous and muscle arbors were similar; both types first entered the spinal gray matter at stage 28-29 (embryonic day (E) 6). Differences in projections were first observed by late stage 34 (E8.5): muscle afferent collaterals extended almost unbranched to the level of motoneuronal dendrites while cutaneous afferents branched frequently and remained within the dorsal horn. Projections of putative small caliber axons into laminae 1 and 2, located laterally in the chick, did not develop until E13-14.
在鸡胚中，用碘化丙啶（DiI）分别标记肌肉和皮肤神经，以研究脊髓中感觉传入神经分支的发育。最初，皮肤和肌肉分支相似；两种类型在第28 - 29阶段（胚胎日（E）6）首次进入脊髓灰质。在第34阶段后期（E8.5）首次观察到投射差异：肌肉传入侧支几乎无分支地延伸到运动神经元树突水平，而皮肤传入神经频繁分支并保留在背角内。假定的小口径轴突向位于鸡侧面的第1和第2层的投射直到E13 - 14才发育。
