Holzegel K
Berufsdermatosen. 1976;24(6):152-5.
Contact-allergy eczemas due to dichloropropiophenone. Following an exposition to p-beta-dichloropropiophenone (DCP) of less than one year nine skilled chemical plant workers were taken ill with an eczema from contact allergy, particularly badly seizing their faces, necks, hands and forearms. In all workers in question has been recognized a job connected skin disease with bodily impairment of 20 to 30%. The test concentration of DCP was determined at 0.01% (testing vehicle: oil). Nonexposed persons showed response only at 0.5% DCP concentration (50 times higher percentage!) by falling sick of an uncomplicated irritation erythema, strickly localized. With regard to the almost obligatory tendency towards sensitization there must be strict observation of the stringent measures of a labour protection, and moreover, in the future there should be established a closed system of automatic control.
二氯丙酰苯所致接触性变应性湿疹。9名熟练化工厂工人在接触对-β-二氯丙酰苯(DCP)不到一年后,患上了接触性变应性湿疹,面部、颈部、手部和前臂受累尤其严重。所有这些工人均被认定患有与工作相关的皮肤病,身体损伤程度为20%至30%。DCP的测试浓度确定为0.01%(测试载体:油)。未接触者仅在DCP浓度为0.5%(高出50倍!)时出现反应,表现为单纯刺激性红斑,严格局限于局部。鉴于几乎必然的致敏倾向,必须严格遵守严格的劳动保护措施,此外,未来应建立一个封闭的自动控制系统。