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通过含有脱氧核糖核酸的培养黏液实现奈瑟菌的种间转化。

Interspecific transformation of Neisseria by culture slime containing deoxyribonucleate.

作者信息

CATLIN B W

出版信息

Science. 1960 Feb 26;131(3400):608-10. doi: 10.1126/science.131.3400.608-a.

DOI:10.1126/science.131.3400.608-a
PMID:13848178
Abstract

Genetic change of Neisseria meningitidis is elicited by deoxyribonucleate preparations obtained from N. sicca. Such interspecific transformation is effected not only by deoxyribonucleate obtained from cells by conventional methods but also by crude deoxyribonucleate-containing slime which accumulates without experimental intervention in some cultures incubated for a period as short as 44 hours.

摘要

从干燥奈瑟菌获得的脱氧核糖核酸制剂可引发脑膜炎奈瑟菌的基因变化。这种种间转化不仅可由通过传统方法从细胞中获得的脱氧核糖核酸实现，还可由在短至44小时的培养后，在未进行实验干预的情况下积累的含脱氧核糖核酸的粗制黏液实现。

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