Wernert N, Albrech M, Sesterhenn I, Goebbels R, Bonkhoff H, Seitz G, Inniger R, Remberger K
Institute of Pathology, University of the Saarland, Homburg/Saar, FRG.
Eur Urol. 1992;22(1):64-9. doi: 10.1159/000474724.
Using immunostaining for prostate-specific antigen (PSA) and prostatic acid phosphatase (PAP), we can demonstrate prostate-analogous periurethral glands (the 'female prostate') in 66.7% of 33 cases. Histomorphologically, these glands resemble strongly the male prostate glands before puberty. They remain immature throughout life from the fetal period up to advanced age obviously because of a lack of an androgenic stimulus. The glands have long ducts leading into the urethra. A proper stroma component is missing. The immunohistochemical behavior of these glands also corresponds widely to that of the male prostate glands before puberty. No indications can be found for a proper biological function.
利用前列腺特异性抗原（PSA）和前列腺酸性磷酸酶（PAP）免疫染色，我们在33例中的66.7%中发现了类似前列腺的尿道周围腺体（“女性前列腺”）。组织形态学上，这些腺体与青春期前的男性前列腺极为相似。从胎儿期到高龄，它们终生都未成熟，显然是因为缺乏雄激素刺激。这些腺体有长导管通向尿道。缺少合适的间质成分。这些腺体的免疫组化表现也与青春期前男性前列腺的表现广泛对应。未发现其具有正常生物学功能的迹象。
