[病例报告；5'-脱氧氟尿苷治疗伴有多发肝转移的胃癌]
[A case report; 5'-DFUR reduced gastric cancer with multiple liver metastasis].
作者信息
Kurimoto N, Yasuzawa Y, Itoh N, Tamura T, Yoshimoto I
机构信息
Dept. of Surgery, Yanai National Hospital, Japan.
出版信息
Gan To Kagaku Ryoho. 1992 Jul;19(7):1067-70.
We describe a case of gastric cancer with multiple liver metastasis that clearly decreased in size after administration of 5'-DFUR. The patient (a 63-year-old male) was inoperable because of multiple liver metastasis. 5'-DFUR 600 mg/day reduced the size of the multiple liver tumors (reduction rate 90%, partial response for four months), but the gastric tumor was unaltered. A rapid decrease in alkali-phosphatase indicated reduction of the liver tumors only one week after the initiation of 5'-DFUR.
我们描述了一例伴有多发肝转移的胃癌患者，在给予5'-脱氧氟尿苷（5'-DFUR）后，肝转移灶明显缩小。该患者（63岁男性）因多发肝转移而无法手术。每天服用600毫克5'-DFUR可使多发肝肿瘤缩小（缩小率90%，部分缓解持续四个月），但胃肿瘤未发生变化。开始服用5'-DFUR仅一周后，碱性磷酸酶迅速下降表明肝肿瘤缩小。
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