Panzer J D, Poche W, Meek T J, Derbes V J, Atkinson W
Cutis. 1977 Jan;19(1):109-11.
Tetracycline was compared to clindamycin as adjunctive therapy in the treatment of moderate to moderately severe acne under double-blind controlled conditions. Both antibiotics were efficacious and differences were not appreciable. Lesion counts of both comedones and pustules were reduced and clinical improvement was noted in the majority of subjects. Side effects were not a problem. The place of clindamycin in the therapeutic armamentarium of the dermatologist is discussed.
在双盲对照条件下，对四环素和克林霉素作为辅助疗法治疗中度至中度重度痤疮进行了比较。两种抗生素均有效，差异不明显。粉刺和脓疱的皮损计数均减少，大多数受试者的临床症状有所改善。副作用不是问题。本文还讨论了克林霉素在皮肤科医生治疗药物中的地位。
