Ryan R J, Gibson T, Fogelman I
Department of Nuclear Medicine, Guy's Hospital, London, UK.
Nucl Med Commun. 1992 Jul;13(7):497-502. doi: 10.1097/00006231-199207000-00004.
Bone scintigraphy with single photon emission computed tomography (SPECT) offers improved lesion detection and localization when compared to conventional planar imaging. The SPECT findings were investigated in 80 consecutive patients (aged 18-70 years, median 44) referred to a rheumatology outpatient clinic with low back pain persisting for more than 3 months. Lesions of the lumbar spine were demonstrated in 60% of patients using SPECT but in only 35% with planar imaging. Fifty-one per cent of all lesions were only detected by SPECT, and lesions visualized on SPECT could be precisely localized to the vertebral body, or different parts of the posterior elements. Fifty per cent of lesions involved the facetal joints of which almost 60% were identified on SPECT alone. X-rays of the lumbar spine, with posterior oblique views, failed to demonstrate abnormalities corresponding to almost all SPECT posterior element lesions although it identified abnormalities corresponding to over 60% of anterior SPECT lesions. Computed tomography (CT) was performed in 30 patients with a SPECT lesion and sites of facetal joint activity corresponded to facetal osteoarthritis in 82%. It is concluded that bone scintigraphy with SPECT in patients with chronic low back pain demonstrates many lesions not seen with either X-ray or conventional planar imaging. In addition anatomical localization is greatly enhanced with bone SPECT. The technique offers improved diagnosis in a group of patients often difficult to evaluate, and in particular a means of detecting apophyseal joint pathology which may be responsive to treatment.
与传统平面成像相比,单光子发射计算机断层扫描(SPECT)骨闪烁显像能提高病变的检测和定位能力。对80例连续转诊至风湿病门诊的患者(年龄18 - 70岁,中位年龄44岁)进行了研究,这些患者均有持续超过3个月的下背痛。使用SPECT检查时,60%的患者显示有腰椎病变,而平面成像仅能发现35%的患者有病变。所有病变中有51%仅通过SPECT才能检测到,SPECT上显示的病变能够精确地定位到椎体或后部结构的不同部位。50%的病变累及小关节,其中近60%仅在SPECT上被识别。腰椎后前斜位X线片未能显示与几乎所有SPECT后部结构病变相对应的异常,尽管它能识别超过60%的SPECT前部病变对应的异常。对30例有SPECT病变的患者进行了计算机断层扫描(CT),其中82%的小关节活动部位符合小关节骨关节炎。结论是,对于慢性下背痛患者,SPECT骨闪烁显像能显示出许多X线或传统平面成像未发现的病变。此外,骨SPECT能大大增强解剖定位。该技术为一组通常难以评估的患者提供了更好的诊断方法,特别是一种检测可能对治疗有反应的椎间关节病变的手段。