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单光子发射计算机断层扫描(SPECT)扫描在识别可能从关节突关节注射中获益的背痛方面的价值。

The value of SPECT scans in identifying back pain likely to benefit from facet joint injection.

作者信息

Dolan A L, Ryan P J, Arden N K, Stratton R, Wedley J R, Hamann W, Fogelman I, Gibson T

机构信息

Clinical Rheumatology Unit, Guy's Hospital, London.

出版信息

Br J Rheumatol. 1996 Dec;35(12):1269-73. doi: 10.1093/rheumatology/35.12.1269.

Abstract

Lumbar facet disease is sometimes implicated in low back pain. Identification is difficult and this may account for a variable response. Single photon emission computerized tomography (SPECT) is a scanning technique which enables localization of facet joint pathology. We determined whether recognition of facet disease by this method improved the response to corticosteroid injection treatment. Fifty-eight patients with low back pain and displaying accepted clinical criteria for facet joint disease were evaluated by SPECT. Twenty-two had facetal uptake of isotope. These and the tender facet joints of 36 scan-negative patients were injected with 40 mg methylprednisolone and 1 ml 1% lignocaine under X-ray control. Pain was assessed by a blind observer using the McGill questionnaire (MGQ), Present Pain Intensity score (PPI) and a Visual Analogue Scale (VAS). VAS, PPI and MGQ were reduced in the scan-positive patients at 1 month (P = 0.05, P = 0.0005, P = 0.005) and MGQ at 3 months (P = 0.01), whilst scan-negative patients were unchanged. The percentage of scan-positive patients who reported improvement was 95% at 1 month and 79% at 3 months, significantly greater than the control group (P = 0.0005, P = 0.01). Within 6 months, pain improvement in the SPECT-positive group was no longer statistically significant. Tenderness did not correlate with increased uptake on SPECT scan. Osteoarthritis of the facets was more common in the SPECT-positive patients (P < 0.001), but did not correspond with sites of increased uptake on SPECT scan. These results suggest that SPECT can enhance the identification of back pain sufferers likely to obtain short-term benefit from facet joint injection.

摘要

腰椎小关节疾病有时与腰痛有关。其诊断困难,这可能是导致治疗反应不一的原因。单光子发射计算机断层扫描(SPECT)是一种能够定位小关节病变的扫描技术。我们研究了通过这种方法识别小关节疾病是否能改善皮质类固醇注射治疗的效果。对58例有腰痛且符合公认的小关节疾病临床标准的患者进行了SPECT评估。22例患者的小关节有同位素摄取。在X线控制下,对这些患者以及36例扫描阴性患者的压痛小关节注射40mg甲泼尼龙和1ml 1%利多卡因。由一名盲法观察者使用麦吉尔问卷(MGQ)、当前疼痛强度评分(PPI)和视觉模拟量表(VAS)评估疼痛。扫描阳性患者在1个月时VAS、PPI和MGQ降低(P = 0.05,P = 0.0005,P = 0.005),3个月时MGQ降低(P = 0.01),而扫描阴性患者则无变化。报告有改善的扫描阳性患者比例在1个月时为95%,3个月时为79%,显著高于对照组(P = 0.0005,P = 0.01)。6个月内,SPECT阳性组的疼痛改善不再具有统计学意义。压痛与SPECT扫描上摄取增加无关。小关节骨关节炎在SPECT阳性患者中更常见(P < 0.001),但与SPECT扫描上摄取增加的部位不对应。这些结果表明,SPECT可以提高对可能从小关节注射中获得短期益处的背痛患者的识别。

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