Stein D J, Hollander E, Anthony D T, Schneier F R, Fallon B A, Liebowitz M R, Klein D F
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York 10032.
J Clin Psychiatry. 1992 Aug;53(8):267-71.
Paraphilias and related disorders have recently been thought of as sexual addictions. However, it has also been argued that these disorders are sexual compulsions. The question arises as to whether these disorders and obsessive compulsive disorder respond in the same way to pharmacotherapy.
We retrospectively reviewed outcome in 13 patients who presented with sexual symptoms and were treated with serotonin reuptake blockers. Symptoms were divided into paraphilias, nonparaphilic sexual addictions, and sexual obsessions.
Paraphilias had the least improvement, while sexual obsessions had the best response to medication.
Paraphilias and related disorders may be less responsive than sexual obsessions or compulsions to serotonin reuptake blockers. Perhaps paraphilias and related disorders are on the impulsive rather than the compulsive end of the spectrum of obsessive compulsive disorders. Controlled trials are, however, necessary to replicate these preliminary findings.
性偏好障碍及相关疾病近来被视为性成瘾。然而，也有人认为这些疾病是性冲动行为。问题在于这些疾病与强迫症对药物治疗的反应是否相同。
我们回顾性分析了13例出现性症状并接受5-羟色胺再摄取阻滞剂治疗的患者的治疗结果。症状分为性偏好障碍、非性偏好性成瘾和性强迫观念。
性偏好障碍改善最少，而性强迫观念对药物反应最佳。
性偏好障碍及相关疾病对5-羟色胺再摄取阻滞剂的反应可能不如性强迫观念或性冲动行为。或许性偏好障碍及相关疾病处于强迫症谱系的冲动性一端而非强迫性一端。然而，需要对照试验来重复这些初步发现。
