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[溃疡性结肠炎与淀粉样变性。1例病例报告及文献复习]

[Ulcerative colitis and amyloidosis. Presentation of a case and review of the literature].

作者信息

Triviño A, Sánchez Lombraña J L, Linares A, Pérez R, Herrero Zapatero A, Rodrigo L

机构信息

Servicio de Anatomía Patológica y Aparato Digestivo, Hospital Covadonga, Oviedo.

出版信息

Rev Esp Enferm Dig. 1992 Aug;82(2):117-20.

PMID:1389545
Abstract

A case of ulcerative colitis associated with secondary amyloidosis in a 62-year-old man who died from septic shock and pneumonia complicating head injury is reported. Amyloid deposition was incidentally found at autopsy. Proteinuria and hepatomegaly discovered a few days before his death were the only signs of amyloidosis. The postmortem examination showed chronic ulcerative colitis (remitting form) with pseudo-polyps and amyloid deposition in the liver, spleen, pancreas, rectum, adrenals and kidneys. Although secondary amyloidosis complicating with Crohn's disease has been frequently reported, amyloidosis associated with ulcerative colitis has been exceptionally described and only 10 cases have been collected from the literature.

摘要

报告了一例62岁男性溃疡性结肠炎合并继发性淀粉样变性病的病例,该患者死于败血性休克及并发于头部损伤的肺炎。淀粉样沉积是在尸检时偶然发现的。死前几天发现的蛋白尿和肝肿大是淀粉样变性病的唯一体征。尸检显示为慢性溃疡性结肠炎(缓解型)伴有假息肉,且在肝脏、脾脏、胰腺、直肠、肾上腺和肾脏中有淀粉样沉积。虽然克罗恩病合并继发性淀粉样变性病已有很多报道,但溃疡性结肠炎相关的淀粉样变性病仅有特殊病例描述,且从文献中仅收集到10例。

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Rev Esp Enferm Dig. 1992 Aug;82(2):117-20.
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