大鼠胰腺胆囊收缩素（CCK）释放肽（监测肽）及胰腺分泌性胰蛋白酶抑制剂（PSTI）编码基因的分子克隆与特性分析

Molecular cloning and characterization of genes encoding rat pancreatic cholecystokinin (CCK)-releasing peptide (monitor peptide) and pancreatic secretory trypsin inhibitor (PSTI).

作者信息

Tsuzuki S, Miura Y, Fushiki T, Oomori T, Satoh T, Natori Y, Sugimoto E

机构信息

Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan.

出版信息

Biochim Biophys Acta. 1992 Sep 24;1132(2):199-202. doi: 10.1016/0167-4781(92)90012-o.

DOI:10.1016/0167-4781(92)90012-o

Abstract

The genes encoding a rat pancreatic cholecystokinin (CCK)-releasing peptide (monitor peptide) and its structurally related peptide, rat pancreatic secretory trypsin inhibitor (PSTI), have been isolated and sequenced. The two genes share extremely high sequence similarity in the 5' flanking regions, suggesting that these regions may be responsible for the characteristic coordinate expression of the two peptides.

摘要

编码大鼠胰腺胆囊收缩素（CCK）释放肽（监测肽）及其结构相关肽——大鼠胰腺分泌型胰蛋白酶抑制剂（PSTI）的基因已被分离并测序。这两个基因在5'侧翼区域具有极高的序列相似性，表明这些区域可能负责这两种肽的特征性协同表达。

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