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[产志贺毒素大肠杆菌O157引起的肠胃炎。2例病例报告]

[Gastroenteritis caused by verotoxin-producing Escherichia coli O157. Presentation of 2 cases].

作者信息

Elcuaz R, Pena M J, Cañas A, García P, Prats G, Lafarga B

机构信息

Servicio de Microbiología y Parasitología, Hospital Nuestra Señora del Pino, Las Palmas de Gran Canaria.

出版信息

Enferm Infecc Microbiol Clin. 1992 Jun-Jul;10(6):349-51.

PMID:1391018
Abstract

Verotoxin-producing Escherichia coli strains have been associated with acute hemorrhagic colitis since 1982. We have systematically investigated this pathogen in our laboratory, in all stool samples submitted for culture during a fourteen month period, by using MacConkey sorbitol agar to isolate non sorbitol fermenting Escherichia coli strains. Coated latex particles with an antiserum against Escherichia coli O157 were used to detect O157 serogroup Escherichia coli. A completed serological study and verotoxin assay was performed in all positive strains. We have found two non-related cases of verotoxigenic Escherichia coli infection in two children. In one case, the main clinical picture was an acute hemorrhagic colitis and the other one was a diarrhea without presence of blood, with fever and vomiting. Both cases improved without antimicrobial treatment. No systemic complications appeared in any of the cases during the infection. The infection incidence was 0.07% of all positive stool cultures. The few documented cases of this infection in our country should encourage to investigate this pathogen in order to know its real incidence in our environment.

摘要

自1982年以来,产志贺毒素大肠杆菌菌株一直与急性出血性结肠炎有关。在14个月的时间里,我们实验室对所有送检培养的粪便样本,通过使用麦康凯山梨醇琼脂来分离非山梨醇发酵大肠杆菌菌株,对这种病原体进行了系统研究。用抗大肠杆菌O157抗血清包被的乳胶颗粒来检测O157血清型大肠杆菌。对所有阳性菌株进行了完整的血清学研究和志贺毒素检测。我们在两名儿童中发现了两例无关的产志贺毒素大肠杆菌感染病例。一例主要临床表现为急性出血性结肠炎,另一例为无血腹泻,并伴有发热和呕吐。两例均未经抗菌治疗而好转。感染期间,任何一例均未出现全身并发症。感染发生率占所有阳性粪便培养物的0.07%。我国这种感染的记录病例很少,应鼓励对这种病原体进行调查,以了解其在我国环境中的实际发生率。

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