Sölder B, Allerberger F, Eigentler A, Köfler D, Larcher C, Dierich M P, Rowe B
Department of Paediatrics, University of Innsbruck, Austria.
Z Gastroenterol. 1993 Jun;31(6):388-91.
To determine the prevalence of Vero cytotoxin-producing Escherichia coli (VTEC) serotype O157 associated diarrhea in the Austrian patient population, we surveyed all stool specimens of liquid consistency submitted to the Federal Public Health Laboratory (FPHL) in Innsbruck for 2 years for this organism. This laboratory serves a population of approximately 1 Million people. Of 5,265 stool specimens, 7 yielded O157 VTEC. Five isolates of E. coli O157 phage type 32, VT2 were cultured from specimens received during a three day period from residents in the county of Schwaz. During the investigation of this "outbreak" E. coli O157 strains were also isolated from two household contacts. Only 1 out of 8 persons with E. coli O157 diarrhea had bloody stools, although 5 of 7 tested specimens (= 71%) also yielded Campylobacter jejuni. None of our patients received antimicrobial therapy directed against E. coli O157 (one child had josamycin). There were no fatalities and no cases of hemolytic uremic syndrome (follow up period: 6 months). Consumption of hamburger, roast beef, and unpasteurized milk was not confirmed in this study. In Austria, no O157 VTEC strain was isolated till June 1992, although at the FPHL in Innsbruck stool specimens of liquid consistency were cultured for this organism since January 1991.
为确定奥地利人群中产生志贺毒素的大肠杆菌（VTEC）O157血清型相关腹泻的患病率，我们调查了两年间提交至因斯布鲁克联邦公共卫生实验室（FPHL）的所有液态粪便样本中该菌的情况。该实验室服务于约100万人口。在5265份粪便样本中，有7份检出O157 VTEC。从施瓦茨县居民在三天内提交的样本中培养出5株大肠杆菌O157噬菌体32型、VT2型菌株。在对此次“疫情”的调查中，还从两名家庭接触者中分离出大肠杆菌O157菌株。8例大肠杆菌O157腹泻患者中只有1例出现血便，不过7份检测样本中有5份（71%）也检出空肠弯曲菌。我们的患者均未接受针对大肠杆菌O157的抗菌治疗（1名儿童使用了交沙霉素）。无死亡病例，也无溶血尿毒综合征病例（随访期6个月）。本研究未证实有食用汉堡、烤牛肉和未杀菌牛奶的情况。在奥地利，直到1992年6月才分离出O157 VTEC菌株，尽管自1991年1月起因斯布鲁克的FPHL就对液态粪便样本培养该菌。
