Nguyen T, Avril M F, Charpentier P, Guillaume C, Margulis A, Prade M
Service de dermatologie, Institut Gustave-Roussy, Villejuif, France.
Bull Cancer. 1992;79(3):291-6.
Sixteen patients with clinical stage II melanoma of unknown primary site (regional lymph node metastasis) were followed up between 1978 and 1988. The 5-year survival rate was 47%. These results seem to parallel those for stage II disease with known primary tumor sites, as has been observed in other data from the literature. The hypotheses put forward to explain such lesions are the spontaneous regression of the primary tumor, and the onset of primary malignant melanoma in the lymph nodes.
1978年至1988年间，对16例原发部位不明（区域淋巴结转移）的临床II期黑色素瘤患者进行了随访。5年生存率为47%。这些结果似乎与已知原发肿瘤部位的II期疾病的结果相似，正如从文献中的其他数据所观察到的那样。为解释此类病变而提出的假说是原发肿瘤的自发消退以及淋巴结中原发性恶性黑色素瘤的发生。
