Gross S B, Robertson W W, Lange B J, Bunin N J, Drummond D S
Children's Hospital of Philadelphia, Pennsylvania.
Clin Orthop Relat Res. 1992 Oct(283):276-80.
The presentation of Hodgkin's disease as a primary bony lesion is unusual. Seventeen such cases have been reported, only three of which appear in the orthopedic literature. The prognosis for survival in these patients is poor, possibly because of difficulty in arriving at the correct early diagnosis. In two adolescent girls (ages 12 and 17) with primary Hodgkin's disease of bone, the diagnosis was made with uncertainty or delay. One of the patients died and the other has progressive disease, two and one-half years after the diagnosis was established. Earlier recognition may lead to better outcomes.
霍奇金病以原发性骨病变形式出现的情况并不常见。已有17例此类病例报告，其中仅有3例出现在骨科文献中。这些患者的生存预后较差，可能是因为难以做出正确的早期诊断。在两名患有原发性骨霍奇金病的青春期女孩（年龄分别为12岁和17岁）中，诊断存在不确定性或延迟。其中一名患者死亡，另一名患者在确诊两年半后病情进展。更早的识别可能会带来更好的结果。
