Langley Clare R, Garrett Simon J W, Urand Jill, Kohler Janice, Clarke Nick M P
Orthopaedic Department, Basingstoke and North Hampshire Foundation Trust, Aldermaston Road, Basingstoke, Hampshire, RG24 9NA, UK.
World J Surg Oncol. 2008 Mar 17;6:34. doi: 10.1186/1477-7819-6-34.
Hodgkin's disease (HD) most commonly presents with progressive painless enlargement of peripheral lymph nodes, especially around the cervical region. A few children have systemic symptoms and weight loss. At the time of diagnosis, osseous involvement is uncommon
A case is described of Primary Multifocal Osseous Hodgkin's Lymphoma in a seven-year-old boy. He presented with a painful swelling in the sternum, and further investigations revealed deposits in his L1 vertebra, the left sacro-iliac joint and the right acetabulum.
The clinical, radiological and histological features of this disease can mimic other medical conditions, including Tuberculosis, making the diagnosis difficult and often leading to delays in treatment. This is a very rare condition and we believe this to be the youngest reported case in the literature.
霍奇金淋巴瘤（HD）最常见的表现是外周淋巴结进行性无痛性肿大，尤其是颈部周围。少数儿童有全身症状和体重减轻。在诊断时，骨骼受累并不常见。
描述了一名七岁男孩原发性多灶性骨霍奇金淋巴瘤的病例。他表现为胸骨疼痛性肿胀，进一步检查发现L1椎体、左骶髂关节和右髋臼有病灶。
该疾病的临床、放射学和组织学特征可类似于其他病症，包括结核病，这使得诊断困难，且常常导致治疗延误。这是一种非常罕见的病症，我们认为这是文献中报道的最年轻病例。
