Chan K W, Rosen G, Miller D R, Tan C T
Am J Pediatr Hematol Oncol. 1982 Spring;4(1):11-7.
Bone involvement of Hodgkin's disease usually occurs late in the course of the illness, together with extensive nodal involvement. In the past 5 years, we have seen four adolescents with Hodgkin's disease who presented with primary bone lesions. All had disseminated lymphoid involvement when the final diagnosis was made 3-11 months later. A review of the literature showed 13 more cases of similar presentation. The patient characteristics are discussed and the diagnostic difficulties are emphasized. Hodgkin's disease should be considered in the differential diagnosis of primary osseous malignancies.
霍奇金淋巴瘤的骨受累通常发生在病程晚期，同时伴有广泛的淋巴结受累。在过去5年中，我们诊治了4例以原发性骨病变为表现的青少年霍奇金淋巴瘤患者。3至11个月后最终确诊时，所有患者均有弥漫性淋巴组织受累。文献复习显示还有13例类似表现的病例。本文讨论了患者特征并强调了诊断难点。在原发性骨恶性肿瘤的鉴别诊断中应考虑霍奇金淋巴瘤。
