Ison C A, Whitaker L, Renton A
Department of Medical Microbiology, St Mary's Hospital Medical School, Paddington, London.
Epidemiol Infect. 1992 Oct;109(2):265-71. doi: 10.1017/s0950268800050214.
One hundred and three known sexual-contact pairs of patients with culture-proven gonorrhoea who attended St Mary's Hospital, London between May 1989 and February 1991 were identified. All isolates from these patients were serotyped and auxotyped and compared for type concordance within sexual-contact pairs. Serotype was concordant in 80 (78%) of 103 sexual-contact pairs, auxotype in 88 (85%) and auxotype/serovar (A/S) class in 66 (64%) on the first screening. All pairs of isolates showed concordance in both serotype and auxotype when typing was repeated using a single set of serotyping reagents and of auxotyping media. Seventeen serovars, 9 auxotypes and 36 A/S classes were found in this population. Our results suggest that both serotyping and auxotyping may be used as markers to allow tracing of sexual-contact pairs, but that a single set of reagents should be used to ensure maximum reliability.
1989年5月至1991年2月期间,在伦敦圣玛丽医院就诊的103对经培养证实患有淋病的已知性接触患者被识别出来。对这些患者的所有分离株进行血清分型和辅助分型,并在性接触配对中比较类型一致性。初次筛查时,103对性接触配对中有80对(78%)血清型一致,88对(85%)辅助型一致,66对(64%)辅助型/血清型(A/S)类别一致。当使用一组血清分型试剂和辅助分型培养基重复分型时,所有分离株对在血清型和辅助型上均显示一致。在该人群中发现了17种血清型、9种辅助型和36种A/S类别。我们的结果表明,血清分型和辅助分型都可作为标记物用于追踪性接触配对,但应使用一组试剂以确保最大可靠性。