红豆杉中毒导致的意外猝死。五例报告并文献复习
Sudden unexpected death due to Taxus poisoning. A report of five cases, with review of the literature.
作者信息
Van Ingen G, Visser R, Peltenburg H, Van Der Ark A M, Voortman M
机构信息
National Forensic Pathology, Rijswijk, The Netherlands.
出版信息
Forensic Sci Int. 1992 Sep;56(1):81-7. doi: 10.1016/0379-0738(92)90150-u.
The toxicity of yew (Taxus) has been known since antiquity. However, in the past 31 years, to our knowledge only six cases of Taxus poisoning have been reported in the literature. In the present paper we add five cases. From a forensic point of view, intoxication with Taxus has three important aspects: (i) the clinical presentation, which among other causes should suggest Taxus intoxication; (ii) the fact that the diagnosis may often be easily made by examination of the contents of stomach, duodenum and small bowel and (iii) the widespread availability in the near future of Taxol, an anti-neoplastic drug which is an alkaloid extracted from Taxus. The clinical and autopsy findings are summarized, the diagnostic aspects are discussed and the literature concerning Taxus is reviewed.
紫杉的毒性自古以来便为人所知。然而，据我们所知，在过去的31年里，文献中仅报道了6例紫杉中毒病例。在本文中，我们补充了5例。从法医学角度来看，紫杉中毒有三个重要方面：（i）临床表现，在其他病因中应提示紫杉中毒；（ii）通常通过检查胃、十二指肠和小肠内容物即可轻易做出诊断这一事实；（iii）在不久的将来，紫杉醇这种从紫杉中提取的生物碱类抗肿瘤药物将广泛可得。总结了临床和尸检结果，讨论了诊断方面，并对有关紫杉的文献进行了综述。
Zotero 插件