Mendez M F, Ala T, Underwood K L
Department of Neurology, St. Paul-Ramsey Medical Center/University of Minnesota, St. Paul 55101.
J Am Geriatr Soc. 1992 Nov;40(11):1095-9. doi: 10.1111/j.1532-5415.1992.tb01796.x.
To investigate the reliability and validity of free-hand clock drawings, a frequently used measure of constructional apraxia, in patients with Alzheimer's disease.
Survey for the purpose of testing reliability and validity of a new scale.
Memory Disorder Clinic at a university-affiliated hospital in the Upper Midwest.
Forty-six patients were diagnosed with clinically probable dementia of the Alzheimer type after a dementia evaluation, and 26 normal elderly controls were research volunteers without a history of cognitive dysfunction.
Neuropsychological tests, dementia-related scales, and clock drawings rated by a new 20-item Clock Drawing Interpretation Scale. Reliability measures, correlations, and clustering of items in the CDIS.
The CDIS had inter-rater reliability (r = .94), internal consistence (rtt = .95), and reproducibility over a 6-month interval. CDIS scores were significantly correlated with two dementia-related scales and all neuropsychological tests and had the highest correlations with other measures of constructional apraxia. All but four Alzheimer patients (91%) and none of the controls had CDIS scores of 18 or less.
Clinicians may reliably screen patients with Alzheimer's disease with the clock-drawing task, a measure sensitive to deficits in constructional apraxia.
研究在阿尔茨海默病患者中，常用的结构性失用症测量方法——徒手画钟试验的可靠性和有效性。
为测试一种新量表的可靠性和有效性而进行的调查。
中西部一所大学附属医院的记忆障碍门诊。
46例患者在进行痴呆评估后被诊断为临床很可能的阿尔茨海默型痴呆，26名正常老年对照者为无认知功能障碍病史的研究志愿者。
神经心理学测试、痴呆相关量表以及由一个新的20项钟面画解释量表进行评分的钟面画。钟面画解释量表中的信度测量、相关性和项目聚类。
钟面画解释量表具有评分者间信度（r = 0.94）、内部一致性（rtt = 0.95），且在6个月的时间间隔内具有可重复性。钟面画解释量表得分与两个痴呆相关量表以及所有神经心理学测试显著相关，并且与其他结构性失用症测量方法的相关性最高。除4例阿尔茨海默病患者外（91%），所有对照者的钟面画解释量表得分均未达到18分或更低。
临床医生可以通过画钟任务可靠地筛查阿尔茨海默病患者，该任务对结构性失用症缺陷敏感。
