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核糖体失活蛋白和皂草素免疫毒素的免疫学特性。

Immunological properties of ribosome-inactivating proteins and a saporin immunotoxin.

作者信息

Strocchi P, Barbieri L, Stirpe F

机构信息

Dipartimento di Farmacologia, Università di Bologna, Italy.

出版信息

J Immunol Methods. 1992 Oct 19;155(1):57-63. doi: 10.1016/0022-1759(92)90271-t.

DOI:10.1016/0022-1759(92)90271-t
PMID:1401966
Abstract

Antibodies have been raised in rabbits against plant ribosome-inactivating proteins (RIPs) and used to demonstrate cross-reactivity between RIPs from plants belonging to the same family, but little or no cross-reactivity between RIPs from taxonomically unrelated plants. When an immunotoxin consisting of saporin conjugated to bovine IgG was injected into rabbits, the animals formed antibodies against both saporin and bovine IgG.

摘要

已在兔子体内产生了针对植物核糖体失活蛋白(RIPs)的抗体,并用于证明来自同一科植物的RIPs之间存在交叉反应,但分类学上不相关植物的RIPs之间几乎没有交叉反应。当将由与牛IgG偶联的皂草素组成的免疫毒素注射到兔子体内时,动物体内形成了针对皂草素和牛IgG的抗体。

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Immunological properties of ribosome-inactivating proteins and a saporin immunotoxin.核糖体失活蛋白和皂草素免疫毒素的免疫学特性。
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