Goenka P, Chait M, Hitti I F, Glasberg S S, Narasimhan P
Department of Medicine, LaGuardia Hospital, Forest Hills, NY 11375.
J Fam Pract. 1992 Oct;35(4):445-6, 449.
A 75-year-old woman in accelerated-phase chronic myeloid leukemia with hyperleukocytosis presented with acute respiratory distress syndrome. Despite early and aggressive pulmonary support and cytoreductive chemotherapy, the patient died. Autopsy confirmed the presence of the leukostasis syndrome. The clinical, radiologic, pathophysiologic, and therapeutic aspects of this entity are reviewed.
一名75岁处于慢性髓性白血病加速期且白细胞增多的女性患者出现急性呼吸窘迫综合征。尽管给予了早期积极的肺部支持和减积化疗,患者仍死亡。尸检证实存在白细胞淤滞综合征。本文对该疾病实体的临床、放射学、病理生理学及治疗方面进行了综述。