华法林所致皮肤坏死。足部表现。

Coumadin skin necrosis. Pedal manifestations.

作者信息

Viegas G V

机构信息

Reconstructive Foot Service, University of Chicago Hospital, IL.

出版信息

J Am Podiatr Med Assoc. 1992 Sep;82(9):463-70. doi: 10.7547/87507315-82-9-463.

DOI:10.7547/87507315-82-9-463

PMID:1403736

Abstract

The idiosyncratic dermatologic reaction to coumarin-like agents, most notably, Coumadin (warfarin sodium) has been well described in the world's literature. Although the incidence is reported to be less than 0.1% of patients treated with Coumadin, pedal cases tend to be striking and their treatment seemingly tenuous.

摘要

香豆素类药物引起的特异性皮肤反应，最显著的是华法林（华法林钠），在世界文献中已有充分描述。尽管据报道接受华法林治疗的患者中发生率低于0.1%，但足部病例往往较为显著，其治疗似乎也很棘手。