Schreiber V, Pribyl T
Physiol Bohemoslov. 1977(2):129-37.
Male rats were given oestradiol benzoate (1 mg as an aquaeous microcrystal suspension i.m. twice a week), testosterone isobutyrate (0.5 mg as an aquaeous microcrystal suspension i.m. once a week) and dried thyroid (Thyreoidin SPOFA, 0.2% in food), alone or variously combined. Oestradiol raised adenohypophyseal weight, the binding capacity of the adenohypophyseal proteins for thyroxine and the serum ceruloplasmin level. Testosterone and Thyreoidin inhibited all three of these reactions, but when they were administered together there was no summation of their inhibitory action. The nature of the relationships between the three given proteosynthetic reactions is discussed.
给雄性大鼠单独或多种组合给予苯甲酸雌二醇（1毫克，制成水微晶悬液，每周肌肉注射两次）、异丁酸睾酮（0.5毫克，制成水微晶悬液，每周肌肉注射一次）和干燥甲状腺（甲状腺素SPOFA，食物中含0.2%）。雌二醇增加了腺垂体重量、腺垂体蛋白质对甲状腺素的结合能力以及血清铜蓝蛋白水平。睾酮和甲状腺素抑制了所有这三种反应，但当它们一起给药时，其抑制作用没有叠加。讨论了所给三种蛋白质合成反应之间关系的性质。
