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早期断奶对大鼠脂肪组织脂肪酸组成的影响。

Effect of premature weaning on the fatty acid composition of rat adipose tissue.

作者信息

Skottová N, Palkovic M, Macho L

出版信息

Physiol Bohemoslov. 1977(2):97-101.

PMID:140394
Abstract

The authors described the effect of premature weaning on the fatty acid spectrum in the retroperintoneal fat of female rats during ontogenesis. Premature weaning reduced the lower fatty acid content [decanoic acid C 10:0, lauric acid C 12:0, myristic acid C 14:0] in 30- to 90-day-old rats, but in further development no differences between the amount of these fatty acids were observed in suckled and prematurely weaned animals. These changes concurred with the fatty acid composition of the relevant diet (rat milk and a standard laboratory diet). Changes induced in the amount of other acids by premature weaning were not permanent in character, with the exception of stearic acid C 18:0 and linoleic acid C 18:3, which were raised at 720 days in the retroperitoneal fat of prematurely weaned rats. The amount of lower saturated fatty acids fell with advancing age, whereas oleic C 18:1, linolic C 18:2 and linolenic C 18:3 acid rose.

摘要

作者描述了过早断奶对雌性大鼠个体发育过程中腹膜后脂肪脂肪酸谱的影响。过早断奶降低了30至90日龄大鼠体内低级脂肪酸的含量[癸酸C 10:0、月桂酸C 12:0、肉豆蔻酸C 14:0],但在进一步发育过程中,未观察到哺乳和过早断奶动物体内这些脂肪酸含量的差异。这些变化与相关饮食(大鼠乳和标准实验室饮食)的脂肪酸组成一致。过早断奶引起的其他酸含量的变化并非永久性的,硬脂酸C 18:0和亚油酸C 18:3除外,它们在过早断奶大鼠的腹膜后脂肪中于720天时含量升高。低级饱和脂肪酸的含量随年龄增长而下降,而油酸C 18:1、亚油酸C 18:2和亚麻酸C 18:3则上升。

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