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淋巴细胞与成纤维细胞抑素:某些化学性质

Lymphocyte and fibroblast chalones: some chemical properties.

作者信息

Houck J C, Kanagalingam K, Hunt C, Attallah A, Chung A

出版信息

Science. 1977 May 20;196(4292):896-7. doi: 10.1126/science.140460.

DOI:10.1126/science.140460
PMID:140460
Abstract

Experiments with lymphocyte and fibroblast chalones indicate that they are complexed strongly with RNA in tissue extracts; have a molecular weight of less than 10,000 and more than 1,000 daltons, and probably about 5,000 daltons; are strongly cationically charged; and contain mannose and perhaps other carbohydrates.

摘要

对淋巴细胞抑素和成纤维细胞抑素进行的实验表明,它们在组织提取物中与RNA紧密结合;分子量小于10,000道尔顿且大于1,000道尔顿,可能约为5,000道尔顿;带有强阳离子电荷;并且含有甘露糖以及可能的其他碳水化合物。

相似文献

1
Lymphocyte and fibroblast chalones: some chemical properties.淋巴细胞与成纤维细胞抑素:某些化学性质
Science. 1977 May 20;196(4292):896-7. doi: 10.1126/science.140460.
2
The effects of fractions (chalones) obtained from lymphoid organs on lymphocyte proliferation in vitro.从淋巴器官获得的组分(抑素)对体外淋巴细胞增殖的影响。
Agents Actions. 1977 Sep;7(3):327-35. doi: 10.1007/BF01969564.
3
Evidence for a colon chalone.结肠抑素的证据。
J Natl Cancer Inst. 1976 May;56(5):899-902. doi: 10.1093/jnci/56.5.899.
4
Control of fibroblast proliferation.成纤维细胞增殖的控制
Natl Cancer Inst Monogr. 1973 Jul;38:161-70.
5
An endogenous inhibitor of fibroblast proliferation hinders simian virus 40 replication.一种成纤维细胞增殖的内源性抑制剂会阻碍猿猴病毒40的复制。
Naturwissenschaften. 1979 May;66(5):265-6. doi: 10.1007/BF00571612.
6
Screening for specific calf thymus inhibitors (chalones) of T-lymphocyte proliferation.
Hoppe Seylers Z Physiol Chem. 1979 Jun;360(6):735-45. doi: 10.1515/bchm2.1979.360.1.735.
7
The inhibition of fibroblast proliferation by a novel monokine: an in vitro and in vivo study.一种新型单核因子对成纤维细胞增殖的抑制作用:一项体外和体内研究。
J Burn Care Rehabil. 1993 Mar-Apr;14(2 Pt 1):141-7. doi: 10.1097/00004630-199303000-00003.
8
[Tissue-specific regulation of proliferative processes in the tissues normally and in pathology: on the problem of chalones].
Arkh Patol. 1978;40(3):3-13.
9
[Current concepts of lymphocytic chalones as endogenous immunomodulators].
Zh Mikrobiol Epidemiol Immunobiol. 1984 Dec(12):9-17.
10
[Purification and characterization of epidermal G2- and G1-chalones].[表皮G2期和G1期抑素的纯化与特性分析]
Biokhimiia. 1978 Jun;43(6):971-8.

引用本文的文献

1
Purification of kidney epithelial cell growth inhibitors.肾上皮细胞生长抑制剂的纯化
Proc Natl Acad Sci U S A. 1980 Oct;77(10):5989-92. doi: 10.1073/pnas.77.10.5989.
2
[Humoral factors in the regulation of cell proliferation in haematopoiesis. I. Granulopoiesis and lymphopoiesis (author's transl)].[造血过程中细胞增殖调节的体液因素。I. 粒细胞生成和淋巴细胞生成(作者译)]
Klin Wochenschr. 1980 Oct 15;58(20):1117-33. doi: 10.1007/BF01477234.
3
Influence of malaria infection on the elaboration of soluble mediators by adherent mononuclear cells.
疟疾感染对黏附单核细胞分泌可溶性介质的影响。
Infect Immun. 1979 Apr;24(1):151-9. doi: 10.1128/iai.24.1.151-159.1979.
4
Production of autoinhibitory factors by mouse lymphoma cells in vitro and its relationship to thiol dependence.小鼠淋巴瘤细胞在体外产生自抑制因子及其与硫醇依赖性的关系。
Proc Natl Acad Sci U S A. 1978 Apr;75(4):1849-53. doi: 10.1073/pnas.75.4.1849.
5
An endogenous inhibitor of fibroblast proliferation hinders simian virus 40 replication.一种成纤维细胞增殖的内源性抑制剂会阻碍猿猴病毒40的复制。
Naturwissenschaften. 1979 May;66(5):265-6. doi: 10.1007/BF00571612.
6
Tissue-specific inhibitor of lymphocyte proliferation extracted and purified from calf spleen. Biological and chemical properties.
Blut. 1979 Oct;39(4):271-9. doi: 10.1007/BF01013220.
7
The effects of fractions (chalones) obtained from lymphoid organs on lymphocyte proliferation in vitro.从淋巴器官获得的组分(抑素)对体外淋巴细胞增殖的影响。
Agents Actions. 1977 Sep;7(3):327-35. doi: 10.1007/BF01969564.