Fujiuchi S, Matsumoto H, Osanai S, Nakano H, Akiba Y, Morita K, Tsuji T, Imamoto T, Onodera S
First Department of Internal Medicine, Asahikawa Medical College, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1992 Apr;30(4):638-42.
A 57-year-old man was admitted complaining of sleep disturbance. All night polysomnography showed a pattern of obstructive sleep apnea. We performed 201Tl scintigraphy to evaluate hemodynamic change and degree of stress on the right ventricle during sleep, and compared it with a 201Tl scintigram during wakefulness. We recognized 201Tl uptake by the lung in the 201Tl scintigram during sleep, but not during wakefulness. To determine the mechanism of 201Tl uptake by the lung during sleep, we measured lung water content during sleep by double indicator dilution method (Nihon Koden, NTV-1100). We recognized an increase of lung water content during sleep. We consider that the increase of lung water content during sleep is caused by sleep apnea, probably by hemodynamic change due to negative pleural pressure swings during sleep apnea.
一名57岁男性因睡眠障碍入院。整夜多导睡眠图显示为阻塞性睡眠呼吸暂停模式。我们进行了铊-201闪烁扫描，以评估睡眠期间右心室的血流动力学变化和应激程度，并将其与清醒时的铊-201闪烁图进行比较。我们发现在睡眠期间的铊-201闪烁图中肺有铊-201摄取，而清醒时则没有。为了确定睡眠期间肺摄取铊-201的机制，我们采用双指示剂稀释法（日本光电，NTV-1100）测量了睡眠期间的肺含水量。我们发现睡眠期间肺含水量增加。我们认为睡眠期间肺含水量增加是由睡眠呼吸暂停引起的，可能是由于睡眠呼吸暂停期间胸膜负压波动导致的血流动力学变化。
