Abou-Zeid A A, Eissa A I, El-Dewany A I, El-Hamid M M, Fouad M, Fahmi M, Yassein M
Folia Microbiol (Praha). 1977;22(1):47-54. doi: 10.1007/BF02876994.
Three strains of Streptomyces rimosus were grown on four different media. The one suitable for the production of oxytetracycline by Streptomyces rimosus 12907 was modified by black strap molasses, fodder yeast (40% total protein) and rice bran. The volume of the fermentation medium was sealed up in a 1200-litre fermentor aerated with sterile air obtained from a system used in the purification of air. 850 g crude oxytetracycline was obtained when the fermented medium (700 litres) was extracted with 1-butanol.
三株龟裂链霉菌在四种不同培养基上生长。适合龟裂链霉菌12907生产土霉素的培养基用糖蜜、饲料酵母（总蛋白含量40%）和米糠进行了改良。将发酵培养基的体积密封在一个1200升的发酵罐中，用空气净化系统获得的无菌空气进行通气。当用正丁醇萃取700升发酵培养基时，得到了850克粗土霉素。
