Production of oxytetracycline by Streptomyces rimosus 12,907 as an animal feed supplement.

Production of oxytetracycline by Streptomyces rimosus 12907 as an animal feed supplement was achieved with a fermentation medium, containing the following ingredients (g/litre): black strap molasses, 30; fodder yeast, 20; rice bran, 10; KH2PO4, 0.2; and tap water to 1,000 ml. The dry mash, containing oxytetracycline, was 50 g/litre of fermentation medium. The amount of oxytetracycline, present in the dry mash, was about 4.0%. The dry mash, containing oxytetracycline, contained the following amino acids: L-arginine, L-histidine, L-lysine, L-isoleucine, L-leucine, L-phenylalanine, Dl-methionine, and L-tryptophan.